Pagoclone is a pharmaceutical substance that was under development for stuttering until the 2010s and was previously investigated for panic, anxiety, and premature ejaculation. It does not have a benzodiazepine structure, but it operates at the benzodiazepine site.
Although it had some efficacy in panic and stuttering, it was not sufficient to maintain investment, so the drug has never been commercialized.
It has occasionally been sold online, but its use outside of clinical research settings is minimal.
TDC overview page (with references): https://thedrugclassroom.com/video/pagoclone/
Reddit discussion: https://www.reddit.com/r/TheDrugClassroom/comments/8o95nn/pagoclone_what_we_know/
Thank you to Ben/BronzeManul for help with the chemistry section and chemical structures.
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